New Delhi: A group of Indian researchers has found that a substance formed during the process of metabolism of berries and pomegranates in the human gut may help mitigate inflammatory bowel disease (IBD) that afflicts millions of people globally.
IBD is usually marked by chronic intestinal inflammation and does not have any effective remedy at present. The metabolite formed during the breaking down of berries and pomegranates in the gut with the help of gut bacteria boosts certain proteins critical for keeping the gut lining strong. The metabolite helps the cells in gut lining to remain glued to each and not allow toxins to penetrate. The researchers have also found a synthetic version of the metabolite to be effective in laboratory studies.
Illustration showing tightening of gut barrier cells and reduced inflammation due to gut metabolite, by Praveen Kumar Vemula, inStem, India.