New Delhi: A new study by a group of Indian Pediatricians shows that many newborns are protected from Hepatitis B infection by antibodies they receive from the mother and therefore hepatitis B vaccination at birth may not be necessary.
Infants (below 1 year) are most susceptible to this virus accounting for 90% of cases. Therefore, the National Immunization Policy recommends a pragmatic vaccination schedule wherein the vaccine is given at birth for institutional deliveries and at 6 week to children born outside such health-care settings (due to practical inabilities).
This research study, funded by Indian Council of Medical Research (ICMR), was conducted to examine if the birth dose is crucial for attaining full immunity against hepatitis B infection.
For the study, blood samples from 1-5-year old children from five states – Delhi, Rajasthan, Uttar Pradesh, Uttarakhand and Gujarat – were collected to measure antigen and antibodies of Hepatitis B virus. Among these, 880 children were completely immunized and were given a birth dose of hepatitis B vaccine, 686 were completely immunized but were not given a birth dose of hepatitis B vaccine and 844 were unvaccinated. It was found that children who were given complete vaccination (with or without birth-dose of hepatitis B vaccine) had a similar level of protection against infection. This means birth dose may not be necessary for full immunization to this virus.
Hepatitis B, a viral infection which causes liver cirrhosis or liver cancer, is a cause of one lakh deaths per year in India. This disease spreads by contact with infected blood or body fluids and can pass from mother to baby, child to child, through blood transfusions and unprotected sexual contact. Over 40 million Indians are chronically infected with Hepatitis B. Many people can live without symptoms for years and once they realize they have an infection, it is often too late for treatment.